Lactobacillus casei CCFM419 attenuates type 2 diabetes via a gut microbiota dependent mechanism

Gang Wang, Xiangfei Li, Jianxin Zhao, Hao Zhang, Wei Chen

Food & Function · 2017 · 175 citations · 25 references

Concepts

Abstract

CFU of L. casei CCFM419 dramatically increased the abundance of Bacteroidetes and decreased the proportion of Firmicutes at the phylum level, and enriched Bifidobacterium, Lactobacillus, and SCFA-producing bacteria, including Allobaculum and Bacteroides. These findings suggested that L. casei CCFM419 modified the gut flora-SCFA-inflammation/GLP-1 mechanism to ameliorate type 2 diabetes.

References

25