The metabolic syndrome

Robert H. Eckel, KGMM Alberti, Scott M. Grundy, +1

The Lancet

ObesityMetabolic SyndromeBody CompositionMetabolic DisorderDiabetes +5

Obesity is associated with hypothalamic injury in rodents and humans

Joshua P. Thaler, Chun‐Xia Yi, Ellen A. Schur, +16

Journal of Clinical Investigation

Hypothalamic InjuryReactive GliosisHigh-fat DietObesityMetabolic Syndrome +17

Resolvins

Charles N. Serhan, Song Hong, Karsten Gronert, +4

The Journal of Experimental Medicine

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

Xiaoqing Zhang, Guo Zhang, Hai Zhang, +3

Cell

ObesityMetabolic SyndromeInflammationHypothalamic Ikkβ/nf-κbEnergy Homeostasis +6

Consumption of a Fat-Rich Diet Activates a Proinflammatory Response and Induces Insulin Resistance in the Hypothalamus

Cláudio Teodoro de Souza, Eliana P. Araújo, Silvana Bordin, +5

Endocrinology

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

Marciane Milanski, Giovanna Rosa Degasperi, Andressa Coope, +13

Journal of Neuroscience

ImmunologyFatty Acids ProduceInflammatory Response PredominantlyGastrointestinal Peptide HormoneInflammation +19

Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance

Christian Bjørbæk, Joel K. Elmquist, J. Daniel Frantz, +2

Molecular Cell

Gastrointestinal Peptide HormoneSignal TransductionAutoimmune DiseasePotential MediatorMedicine +9

Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1

Makoto Arita, Francesca Bianchini, Júlio Aliberti, +6

The Journal of Experimental Medicine

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

Sriram Krishnamoorthy, Antonio Recchiuti, Nan Chiang, +5

Proceedings of the National Academy of Sciences

Infection regulates pro-resolving mediators that lower antibiotic requirements

Nan Chiang, Gabrielle Fredman, Fredrik Bäckhed, +4

Nature

Bacterial InfectionsAntimicrobial SusceptibilityAntibioticsPro-resolving MediatorsAntibiotic Adjuvant +5