Concepedia

Hypothalamic Inflammation

Hypothalamic Inflammation is a pathological condition characterized by the activation of pro-inflammatory signaling pathways specifically within the hypothalamus, distinguishing it from systemic or peripheral inflammatory processes by its localized impact on central neuroendocrine regulation.

731

Publications

46.7K

Citations

3.4K

Authors

892

Institutions

Publications per year

2017–2026

202

Parents

Publications

731

Obesity is associated with hypothalamic injury in rodents and humans

Joshua P. Thaler, Chun‐Xia Yi, Ellen A. Schur et al. · Journal of Clinical Investigation · 2011 · 1.8K citations

, , +17

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

C A Dinarello, Joseph G. Cannon, S. M. Wolff et al. · The Journal of Experimental Medicine · 1986 · 1.5K citations · Full text

, , +12

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

Xiaoqing Zhang, Guo Zhang, Hai Zhang et al. · Cell · 2008 · 1.3K citations · Full text

, , +16

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

Marciane Milanski, Giovanna Rosa Degasperi, Andressa Coope et al. · Journal of Neuroscience · 2009 · 1.1K citations · Full text

, , +17

Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats.

E Sternberg, J M Hill, George P. Chrousos et al. · Proceedings of the National Academy of Sciences · 1989 · 740 citations · Full text

, , +17

1–5 of 731

Authors

3.4K

  1. LA
    Lı́cio A. Velloso

    Universidade Estadual de Campinas (UNICAMP), Brazil

    27 publications · 3.8K citations

    21

    h-index

  2. JM
    Joseane Morari

    Universidade Estadual de Campinas (UNICAMP), Brazil

    13 publications · 2.7K citations

    12

    h-index

  3. YK
    Yu‐Ming Kang

    Xi'an Jiaotong University, China

    10 publications · 512 citations

    10

    h-index

  4. CY
    Chun‐Xia Yi

    University of Amsterdam, Netherlands

    9 publications · 2.4K citations

    9

    h-index

  5. MM
    Marciane Milanski

    Universidade Estadual de Campinas (UNICAMP), Brazil

    9 publications · 1.7K citations

    9

    h-index

1–5 of 3.4K

Institutions

892

  1. Universidade Estadual de Campinas (UNICAMP)

    Campinas, Brazil

    25 h-index

    302 publications

    33.5K citations

  2. Universidade de São Paulo

    São Paulo, Brazil

    21 h-index

    69 publications

    7.2K citations

  3. University of Washington

    Seattle, United States

    12 h-index

    60 publications

    34.1K citations

  4. University of Amsterdam

    Amsterdam, The Netherlands

    12 h-index

    55 publications

    2K citations

  5. University of Ulsan

    Ulsan, South Korea

    11 h-index

    82 publications

    4.5K citations

  6. Inserm

    Paris, France

    11 h-index

    35 publications

    3.8K citations

  7. University of Michigan

    Ann Arbor, United States

    11 h-index

    32 publications

    3.4K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    66 publications

    3.2K citations

1–8 of 892

Venues

  1. Endocrinology

    49 publications · 3.4K citations

    32

    h-index

  2. 19

    h-index

  3. Brain Research

    27 publications · 1.1K citations

    18

    h-index

  4. Neuroscience Letters

    24 publications · 1.1K citations

    18

    h-index

  5. Brain Behavior and Immunity

    18 publications · 1.2K citations

    17

    h-index

1–5