Concepedia

Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition

B. Sathish Kumar, Kusumoori Ravi, Amit Verma, Kaneez Fatima, Mohammad Hasanain, Arjun Singh, Jayanta Sarkar, Suaib Luqman, Debabrata Chanda, Arvind S. Negi

Bioorganic & Medicinal Chemistry · 2016 · 81 citations · 44 references

Concepts

MedicineOncologyPharmacologyCancer PharmacologyMolecular OncologyStructure-activity RelationshipsEnzyme InhibitionOncology PharmacologyPharmacodynamics Of Anticancer AgentsStructure-activity Relationship AnalysisTopoisomerase InhibitorsAnticancer ActivityAnticancer ChemotherapyCatalytic Topoisomerase InhibitionDna Topoisomerase Ii InhibitionTopoisomerase Ii FunctionTopoisomerase Ii Inhibitors

References

44

Role of poly(ADP-ribose) formation in DNA repair

Masahiko S. Satoh, Tomas Lindahl · Nature · 1992 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +11

Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide

Chyuan-Chuan Wu, Tsai‐Kun Li, Lynn Farh et al. · Science · 2011 · 514 citations

Life Sciences, Molecular Biology, Oncology +14

The cell cycle and cancer

Kathleen Collins, Tyler Jacks, Nikola P. Pavletich · Proceedings of the National Academy of Sciences · 1997 · 383 citations

Natural Sciences, Environmental Social Science, Climate Change Adaptation +16

Topoisomerase levels determine chemotherapy response <i>in vitro</i> and <i>in vivo</i>

Darren J. Burgess, Jason D. Doles, Lars Zender et al. · Proceedings of the National Academy of Sciences · 2008 · 303 citations · Full text

Medicine, Oncology, Pharmacology +13

Fundamentals of experimental pharmacology

Kanwaljit Chopra · Indian Journal of Pharmacology · 2020 · 241 citations · Full text

Medicine, Pharmacology, Experimental Pharmacology +1