Jason D. Doles

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

Jennifer D Bernet, Jason D. Doles, John K. Hall et al. · Nature Medicine · 2014 · 570 citations · Full text

Life Sciences, Biomedical Sciences, Cell Biology +17

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

Mariana G. Tarragó, Claudia C.S. Chini, Karina S. Kanamori et al. · Cell Metabolism · 2018 · 374 citations · Full text

Life Sciences, Biochemistry, Pharmacology +12

Topoisomerase levels determine chemotherapy response <i>in vitro</i> and <i>in vivo</i>

Darren J. Burgess, Jason D. Doles, Lars Zender et al. · Proceedings of the National Academy of Sciences · 2008 · 303 citations · Full text

Medicine, Oncology, Pharmacology +13

Error-prone translesion synthesis mediates acquired chemoresistance

Kun Xie, Jason D. Doles, Michael T. Hemann et al. · Proceedings of the National Academy of Sciences · 2010 · 219 citations · Full text

Medicine, Cancer Biology, Oncology +17

Suppression of Rev3, the catalytic subunit of Polζ, sensitizes drug-resistant lung tumors to chemotherapy

Jason D. Doles, Trudy G. Oliver, Eleanor R. Cameron et al. · Proceedings of the National Academy of Sciences · 2010 · 191 citations · Full text

Medicine, Oncology, Pharmacology +17