Jason D. Doles

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

Jennifer D Bernet, Jason D. Doles, John K. Hall et al. · Nature Medicine · 2014 · 542 citations · Full text

Developmental Biology, Skeletal Muscle, Cell Signaling +14

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

Mariana G. Tarragó, Claudia C.S. Chini, Karina S. Kanamori et al. · Cell Metabolism · 2018 · 355 citations · Full text

Lifespan Extension, Metabolic Syndrome, Aging +12

Topoisomerase levels determine chemotherapy response <i>in vitro</i> and <i>in vivo</i>

Darren J. Burgess, Jason D. Doles, Lars Zender et al. · Proceedings of the National Academy of Sciences · 2008 · 301 citations · Full text

Error-prone translesion synthesis mediates acquired chemoresistance

Kun Xie, Jason D. Doles, Michael T. Hemann et al. · Proceedings of the National Academy of Sciences · 2010 · 218 citations · Full text

Tumor Biology, Biosynthesis, Chemical Transformation +12

Suppression of Rev3, the catalytic subunit of Polζ, sensitizes drug-resistant lung tumors to chemotherapy

Jason D. Doles, Trudy G. Oliver, Eleanor R. Cameron et al. · Proceedings of the National Academy of Sciences · 2010 · 185 citations · Full text

Intrinsic Drug Resistance, Tumor Transplantation Approach, Cisplatin Response +19