Claudia C.S. Chini

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism

Juliana Camacho-Pereira, Mariana G. Tarragó, Claudia C.S. Chini et al. · Cell Metabolism · 2016 · 830 citations · Full text

Age-related Nad Decline, Aging, Mitochondrial Function +10

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

Mariana G. Tarragó, Claudia C.S. Chini, Karina S. Kanamori et al. · Cell Metabolism · 2018 · 355 citations · Full text

Lifespan Extension, Metabolic Syndrome, Aging +12

CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels

Claudia C.S. Chini, Thais Peclat, Gina M. Warner et al. · Nature Metabolism · 2020 · 306 citations · Full text

Inflammation, Immune Cells, Nmn Levels +11

Deleted in breast cancer–1 regulates SIRT1 activity and contributes to high-fat diet–induced liver steatosis in mice

Carlos Escande, Claudia C.S. Chini, Verónica Nin et al. · Journal of Clinical Investigation · 2010 · 186 citations · Full text

Food Restriction Ameliorates the Development of Polycystic Kidney Disease

Gina Warner, Kyaw Zaw Hein, Verónica Nin et al. · Journal of the American Society of Nephrology · 2015 · 178 citations · Full text

Nutrition, Renal Pathology, Immunology +17