Chyuan-Chuan Wu

Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide

Chyuan-Chuan Wu, Tsai‐Kun Li, Lynn Farh et al. · Science · 2011 · 514 citations

Life Sciences, Molecular Biology, Oncology +14

On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs

Chyuan-Chuan Wu, Yi-Ching Li, Wang Ying-Ren et al. · Nucleic Acids Research · 2013 · 189 citations · Full text

Medicine, Oncology, Pharmacology +15

Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry

Ying-Ren Wang, Shin-Fu Chen, Chyuan-Chuan Wu et al. · Nucleic Acids Research · 2017 · 121 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate

Shin-Fu Chen, Nan-Lan Huang, Jung‐Hsin Lin et al. · Nature Communications · 2018 · 70 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ

Chyuan-Chuan Wu, T.J. Baiga, Michael Downes et al. · Proceedings of the National Academy of Sciences · 2017 · 66 citations · Full text

Medicine, Biochemistry, Pharmacology +15