Concepedia

The Mitochondrial Lon Protease Is Required for Age-Specific and Sex-Specific Adaptation to Oxidative Stress

Laura C.D. Pomatto, Caroline Carney, Brenda Shen, Sarah Wong, Kelly Halaszynski, Matthew P. Salomon, Kelvin J.A. Davies, John Tower

Current Biology · 2016 · 211 citations · 37 references

DOIFull text

Open access

Concepts

References

37

Tissue-specific expression and regulation of sexually dimorphic genes in mice

Xia Yang, Eric E. Schadt, Susanna Wang et al. · Genome Research · 2006 · 936 citations · Full text

, , +17

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila

Gerasimos P. Sykiotis, Dirk Bohmann · Developmental Cell · 2008 · 692 citations · Full text

, , +10

Complex I Is the Major Site of Mitochondrial Superoxide Production by Paraquat

Helena M. Cochemé, Michael P. Murphy · Journal of Biological Chemistry · 2007 · 581 citations · Full text

, , +17

Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism

Daniela A. Bota, Kelvin J.A. Davies · Nature Cell Biology · 2002 · 559 citations · Full text

, , +12

The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H<sub>2</sub>O<sub>2</sub> and Plays an Integral Role in Insulin Signal Transduction

Kalyankar Mahadev, Hiroyuki Motoshima, Xiangdong Wu et al. · Molecular and Cellular Biology · 2004 · 506 citations · Full text

, , +15