Fargesin exerts anti-inflammatory effects in THP-1 monocytes by suppressing PKC-dependent AP-1 and NF-ĸB signaling

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

Marco Castagna, Yoshimi Takai, Kozo Kaibuchi et al. · Journal of Biological Chemistry · 1982 · 4.8K citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

Brydon L. Bennett, Dennis T. Sasaki, Brion W. Murray et al. · Proceedings of the National Academy of Sciences · 2001 · 2.6K citations · Full text

Life Sciences, Immunology, Pharmacology +17

Protein kinase C as the receptor for the phorbol ester tumor promoters: sixth Rhoads memorial award lecture.

P M Blumberg · PubMed · 1988 · 430 citations

Life Sciences, Molecular Biology, Oncology +14

Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds

Wasaporn Chanput, Jurriaan J. Mes, Robert A. M. Vreeburg et al. · Food & Function · 2010 · 258 citations

Life Sciences, Immunology, Nutritional Sciences +17

Inhibition of inducible nitric oxide synthase and cyclooxygenase‐2 in lipopolysaccharide‐stimulated RAW264.7 cells by carboxybutyrylated glucosamine takes place via down‐regulation of mitogen‐activated protein kinase‐mediated nuclear factor‐κB signaling

Niranjan Rajapakse, Moon‐Moo Kim, Eresha Mendis et al. · Immunology · 2008 · 127 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14