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Minimizing the risk of chemically reactive metabolite formation of new drug candidates: implications for preclinical drug design

Medicinal ChemistryNew Drug CandidatesPreclinical Drug EvaluationBiochemistryDrug DesignMedicinePreclinical Drug DesignNatural SciencesRational Drug DesignReactive Metabolite FormationMetabolomicsDrug DevelopmentPharmacologyPharmacological IssueDrug DiscoveryPharmaceutical Research