Michael D. Aleo

Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump

Michael D. Aleo, Yi Luo, Rachel Swiss et al. · Hepatology · 2014 · 212 citations · Full text

Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans

Salman R. Khetani, Chitra Kanchagar, Okechukwu Ukairo et al. · Toxicological Sciences · 2012 · 206 citations

Immunology, Micropatterned Cocultures, Bioanalysis +20

Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanistic<i>in vitro</i>Assays

Falgun Shah, Louis Leung, Hugh A. Barton et al. · Toxicological Sciences · 2015 · 139 citations · Full text

Plasma Cmax, Pharmacotherapy, Human Plasma Cmax +23

Mitochondrial dysfunction is an early event in ochratoxin a but not oosporein toxicity to rat renal proximal tubules

Michael D. Aleo · Toxicology and Applied Pharmacology · 1991 · 85 citations

Mitochondrial Function, Biochemistry, Mitochondrial Dysfunction +11

Evaluation of in Vitro Mitochondrial Toxicity Assays and Physicochemical Properties for Prediction of Organ Toxicity Using 228 Pharmaceutical Drugs

Payal Rana, Michael D. Aleo, Mark Gosink et al. · Chemical Research in Toxicology · 2018 · 79 citations

Mitochondrial Dysfunction, Pathology, Toxicological Mechanism +22