Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum

Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome

Stéphane Chavanas, Christine Bodemer, Ariane Rochat et al. · Nature Genetics · 2000 · 838 citations

Mendelian Disorder, Genetic Disorder, Genetics +6

pH Directly Regulates Epidermal Permeability Barrier Homeostasis, and Stratum Corneum Integrity/Cohesion

Jean‐Pierre Hachem, Debra Crumrine, Joachim W. Fluhr et al. · Journal of Investigative Dermatology · 2003 · 522 citations · Full text

Ph Directly, Skin Development, Stratum Corneum Integrity/cohesion +9

Degradation of Corneodesmosome Proteins by Two Serine Proteases of the Kallikrein Family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7

Cécile Caubet, Nathalie Jonca, Maria Brattsand et al. · Journal of Investigative Dermatology · 2004 · 504 citations · Full text

Protein Chemistry, Corneodesmosome Proteins, Protein Function +13

Kallikrein 5 induces atopic dermatitis–like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome

Anaïs Briot, Céline Deraison, Matthieu Lacroix et al. · The Journal of Experimental Medicine · 2009 · 482 citations · Full text

Kallikrein‐mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin

Kenshi Yamasaki, Jürgen Schauber, Alvin B. Coda et al. · The FASEB Journal · 2006 · 456 citations

Microbial Pathogens, Antimicrobial Effects, Immunology +18