Jean‐Pierre Hachem

pH Directly Regulates Epidermal Permeability Barrier Homeostasis, and Stratum Corneum Integrity/Cohesion

Jean‐Pierre Hachem, Debra Crumrine, Joachim W. Fluhr et al. · Journal of Investigative Dermatology · 2003 · 522 citations · Full text

Ph Directly, Skin Development, Stratum Corneum Integrity/cohesion +9

Short-Term Glucocorticoid Treatment Compromises Both Permeability Barrier Homeostasis and Stratum Corneum Integrity: Inhibition of Epidermal Lipid Synthesis Accounts for Functional Abnormalities

Jack Kao, Joachim W. Fluhr, Mao‐Qiang Man et al. · Journal of Investigative Dermatology · 2003 · 360 citations

Inflammation, Functional Abnormalities, Immunology +7

Sustained Serine Proteases Activity by Prolonged Increase in pH Leads to Degradation of Lipid Processing Enzymes and Profound Alterations of Barrier Function and Stratum Corneum Integrity

Jean‐Pierre Hachem, Mao‐Qiang Man, Debra Crumrine et al. · Journal of Investigative Dermatology · 2005 · 310 citations

Biochemistry, Medicine, Natural Sciences +9

Caspase-14 protects against epidermal UVB photodamage and water loss

Geertrui Denecker, Esther Hoste, Barbara Gilbert et al. · Nature Cell Biology · 2007 · 293 citations

Caspase-14 Protects, Signal Transduction, Photochemistry +4

Filaggrin Genotype in Ichthyosis Vulgaris Predicts Abnormalities in Epidermal Structure and Function

Robert Gruber, Peter M. Elias, Debra Crumrine et al. · American Journal Of Pathology · 2011 · 234 citations · Full text

Biology, Skin Development, Genetics +7