Debra Crumrine

pH Directly Regulates Epidermal Permeability Barrier Homeostasis, and Stratum Corneum Integrity/Cohesion

Jean‐Pierre Hachem, Debra Crumrine, Joachim W. Fluhr et al. · Journal of Investigative Dermatology · 2003 · 522 citations · Full text

Ph Directly, Skin Development, Stratum Corneum Integrity/cohesion +9

Short-Term Glucocorticoid Treatment Compromises Both Permeability Barrier Homeostasis and Stratum Corneum Integrity: Inhibition of Epidermal Lipid Synthesis Accounts for Functional Abnormalities

Jack Kao, Joachim W. Fluhr, Mao‐Qiang Man et al. · Journal of Investigative Dermatology · 2003 · 360 citations

Inflammation, Functional Abnormalities, Immunology +7

Sustained Serine Proteases Activity by Prolonged Increase in pH Leads to Degradation of Lipid Processing Enzymes and Profound Alterations of Barrier Function and Stratum Corneum Integrity

Jean‐Pierre Hachem, Mao‐Qiang Man, Debra Crumrine et al. · Journal of Investigative Dermatology · 2005 · 310 citations

Biochemistry, Medicine, Natural Sciences +9

Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens

Tiffany C. Scharschmidt, Mao‐Qiang Man, Yutaka Hatano et al. · Journal of Allergy and Clinical Immunology · 2009 · 282 citations · Full text

Inflammation, Fibrosis, Signal Transduction +14

Commensal microbiota regulates skin barrier function and repair via signaling through the aryl hydrocarbon receptor

Aayushi Uberoi, Casey Bartow‐McKenney, Qi Zheng et al. · Cell Host & Microbe · 2021 · 271 citations · Full text

Inflammation, Microbiota Function, Cutaneous Biology +10