Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Catherine C. Bell, Delilah Hendriks, Sabrina Moro et al. · Scientific Reports · 2016 · 708 citations · Full text

Medicine, Pharmacology, Toxicology +17

Multi-cell type human liver microtissues for hepatotoxicity testing

Simon Messner, Irina Agarkova, Wolfgang Moritz et al. · Archives of Toxicology · 2012 · 318 citations · Full text

Pharmacy, Pharmacology, Toxicology +16

Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans

Salman R. Khetani, Chitra Kanchagar, Okechukwu Ukairo et al. · Toxicological Sciences · 2012 · 207 citations

Pharmacy, Pharmacology, Toxicology +17

GENE EXPRESSION IN HUMAN HEPATOCYTES IN SUSPENSION AFTER ISOLATION IS SIMILAR TO THE LIVER OF ORIGIN, IS NOT AFFECTED BY HEPATOCYTE COLD STORAGE AND CRYOPRESERVATION, BUT IS STRONGLY CHANGED AFTER HEPATOCYTE PLATING

Lysiane Richert, Michael J. Liguori, Catherine Abadie et al. · Drug Metabolism and Disposition · 2006 · 133 citations

Life Sciences, Biochemistry, Molecular Biology +13

FUNCTIONAL EXPRESSION OF SINUSOIDAL DRUG TRANSPORTERS IN PRIMARY HUMAN AND RAT HEPATOCYTES

Émilie Jigorel, Marc Le Vée, Claire Boursier-Neyret et al. · Drug Metabolism and Disposition · 2005 · 104 citations

Pharmacy, Pharmacology, Toxicology +16