Concepedia

Author

Émilie Jigorel

GlaxoSmithKline (United States)

Also Known As

E. Jigorel, Emilie Jigorel, Jigorel, Emilie, Émilie Jigorel

18

Publications

1.1K

Citations

10

H-Index

24

Concepts

All Affiliations

GlaxoSmithKline (United States)GlaxoSmithKline (France)UCB Pharma (Belgium)UCB Pharma (United Kingdom)GlaxoSmithKline (United Kingdom)
ÉJ

About

Émilie Jigorel is an author at GlaxoSmithKline (United States) specializing in cell biology, medicine, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

2

2

252

2

Natural Sciences

2

2

81

3

Biochemistry

2

2

81

4

Cell Biology

2

2

252

5

Cellular Physiology

1

1

184

Émilie Jigorel

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9

Publications

946

Citations

9

H-Index

YearCitations

Differential Regulation of Sinusoidal and Canalicular Hepatic Drug Transporter Expression by Xenobiotics Activating Drug-Sensing Receptors in Primary Human Hepatocytes

Émilie Jigorel, Marc Le Vée, Claire Boursier-Neyret,

Drug Metabolism and Disposition

2006

306

Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line

Marc Le Vée, Émilie Jigorel, Denise Glaise,

European Journal of Pharmaceutical Sciences

2006

184

Binding Mode and Structure–Activity Relationships around Direct Inhibitors of the Nrf2–Keap1 Complex

Eric Jnoff, Claudia Albrecht, John J. Barker,

ChemMedChem

2014

168

FUNCTIONAL EXPRESSION OF SINUSOIDAL DRUG TRANSPORTERS IN PRIMARY HUMAN AND RAT HEPATOCYTES

Émilie Jigorel, Marc Le Vée, Claire Boursier-Neyret,

Drug Metabolism and Disposition

2005

104

Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase

Philip A. Harris, Nicolas Faucher, Nicolas George,

Journal of Medicinal Chemistry

2019

68

Development of a small molecule that corrects misfolding and increases secretion of Z α <sub>1</sub> ‐antitrypsin

David A. Lomas, James A. Irving, Christopher C. Arico-Muendel,

EMBO Molecular Medicine

2021

62

Utility of Drug Depletion-Time Profiles in Isolated Hepatocytes for Accessing Hepatic Uptake Clearance: Identifying Rate-Limiting Steps and Role of Passive Processes

Émilie Jigorel, J. Brian Houston

Drug Metabolism and Disposition

2012

21

Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol <i>O</i> -Methyltransferase

Ingrid P. Buchler, Daniel Akuma, Vinh Au,

Journal of Medicinal Chemistry

2018

20

The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding

John Liddle, Andrew C. Pearce, Christopher C. Arico-Muendel,

Bioorganic & Medicinal Chemistry Letters

2021

13

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