Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals

Abstract

When AAPH is employed as a free radical source, at low concentrations of free, peptide and protein Trp residues, the oxidation is mostly induced by alkoxyl radicals. However, at high concentrations, both peroxyl and alkoxyl radicals are involved.