Concepedia

Phase 2 Trial of Metformin Combined With 5-Fluorouracil in Patients With Refractory Metastatic Colorectal Cancer

Vanessa Costa Miranda, Maria Ignez Braghiroli, Luiza Dib Batista Bugiato Faria, Giovanni M. Bariani, Alexandra Alex, João Evangelista Bezerra Neto, Fernanda Capareli, Jorge Sabbaga, Juliana Ferreira Lobo dos Santos, Paulo M. Hoff,

Clinical Colorectal Cancer · 2016 · 79 citations · 18 references

DOI

Concepts

References

18

The consensus molecular subtypes of colorectal cancer

Justin Guinney, Rodrigo Dienstmann, Xin Wang et al. · Nature Medicine · 2015 · 5.3K citations · Full text

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TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell · 2003 · 3.9K citations · Full text

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Optimal two-stage designs for phase II clinical trials

Richard Simon · Controlled Clinical Trials · 1989 · 3.6K citations

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Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial

Axel Grothey, Eric Van Cutsem, Alberto Sobrero et al. · The Lancet · 2012 · 2.9K citations

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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

Jaekyoung Son, Costas A. Lyssiotis, Haoqiang Ying et al. · Nature · 2013 · 2K citations · Full text

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