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Discovery of novel 7-azaindoles as PDK1 inhibitors

Margarita Wucherer-Plietker, Eugen Merkul, Thomas J. J. Müller, Christina Esdar, Thorsten Knöchel, Timo Heinrich, Hans‐Peter Buchstaller, Hartmut E. Greiner, Dieter Dorsch, Dirk Finsinger,

Bioorganic & Medicinal Chemistry Letters · 2016 · 20 citations · 19 references

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19

A Fast Flexible Docking Method using an Incremental Construction Algorithm

Matthias Rarey, Bernd Krämer, Thomas Lengauer et al. · Journal of Molecular Biology · 1996 · 2.8K citations

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Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1

Richard I. Feldman, James M. Wu, Mark A. Polokoff et al. · Journal of Biological Chemistry · 2005 · 228 citations · Full text

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Gini Coefficient:  A New Way To Express Selectivity of Kinase Inhibitors against a Family of Kinases

Piotr Graczyk · Journal of Medicinal Chemistry · 2007 · 211 citations

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Concise Syntheses of Meridianins by Carbonylative Alkynylation and a Four‐Component Pyrimidine Synthesis

Alexei S. Karpov, Eugen Merkul, Frank Röminger et al. · Angewandte Chemie International Edition · 2005 · 210 citations

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High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site

Ricardo M. Biondi · The EMBO Journal · 2002 · 206 citations · Full text

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