Mark A. Polokoff

Akt/Protein Kinase B Signaling Inhibitor-2, a Selective Small Molecule Inhibitor of Akt Signaling with Antitumor Activity in Cancer Cells Overexpressing Akt

Lin Yang, Han C. Dan, Mei Sun et al. · Cancer Research · 2004 · 422 citations

Antitumor Activity, Chemoprevention Strategy, Pten Mutation +17

Echistatin. A potent platelet aggregation inhibitor from the venom of the viper, Echis carinatus.

Z. Gan, R J Gould, J Jacobs et al. · Journal of Biological Chemistry · 1988 · 363 citations · Full text

Molecular Pharmacology, Allergy, Biochemistry +15

Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1

Richard I. Feldman, James M. Wu, Mark A. Polokoff et al. · Journal of Biological Chemistry · 2005 · 223 citations · Full text

Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms

Nicole Kleinstreuer, Jian Yang, Ellen L. Berg et al. · Nature Biotechnology · 2014 · 208 citations

Phenotypic Screening, Therapeutic Mechanisms, Medicinal Chemistry +13

Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry

Kirk McMillan, Marc Adler, Douglas S. Auld et al. · Proceedings of the National Academy of Sciences · 2000 · 200 citations · Full text