Thorsten Knöchel

Matuzumab Binding to EGFR Prevents the Conformational Rearrangement Required for Dimerization

Judith Schmiedel, Andree Blaukat, Shiqing Li et al. · Cancer Cell · 2008 · 154 citations · Full text

Conformational Rearrangement Required, Protein Folding, Receptor Tyrosine Kinase +8

The crystal structure of anthranilate synthase from <i>Sulfolobus solfataricus</i> : Functional implications

Thorsten Knöchel, A. Ivens, G. Hester et al. · Proceedings of the National Academy of Sciences · 1999 · 114 citations · Full text

The hyperthermostable indoleglycerol phosphate synthase from Thermotoga maritima is destabilized by mutational disruption of two solvent-exposed salt bridges 1 1Edited by R. Huber

Astrid Merz, Thorsten Knöchel, Johan N. Jansonius et al. · Journal of Molecular Biology · 1999 · 72 citations

Mutational Disruption, Biochemistry, Bioenergetics +10

The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5

Kai Schiemann, Dirk Finsinger, Frank T. Zenke et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 63 citations · Full text

Medicinal Chemistry, Mitotic Kinesin-5, Biochemistry +8

Lersivirine, a Nonnucleoside Reverse Transcriptase Inhibitor with Activity against Drug-Resistant Human Immunodeficiency Virus Type 1

Romuald Corbau, Julie Mori, Chris Phillips et al. · Antimicrobial Agents and Chemotherapy · 2010 · 63 citations · Full text

Immunology, Molecular Biology, Pharmacotherapy +16