Concepedia

The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5

Kai Schiemann, Dirk Finsinger, Frank T. Zenke, Christiane Amendt, Thorsten Knöchel, David Bruge, Hans‐Peter Buchstaller, Ulrich Emde, Wolfgang K. Stähle, Soheila Anzali

Bioorganic & Medicinal Chemistry Letters · 2010 · 63 citations · 23 references

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23

Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Thomas U. Mayer, Tarun M. Kapoor, Stephen J. Haggarty et al. · Science · 1999 · 1.7K citations

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Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

Anne Blangy, Heidi A. Lane, Pierre d'Hérin et al. · Cell · 1995 · 963 citations · Full text

, , +14

Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5

Tarun M. Kapoor, Thomas U. Mayer, Margaret Coughlin et al. · The Journal of Cell Biology · 2000 · 731 citations · Full text

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Mitotic spindle organization by a plus-end-directed microtubule motor

Kenneth E. Sawin, Katherine LeGuellec, Michel Philippe et al. · Nature · 1992 · 645 citations

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Chiral Brønsted Acid-Catalyzed Inverse Electron-Demand Aza Diels−Alder Reaction

Takahiko Akiyama, Hisashi Morita, Kohei Fuchibe · Journal of the American Chemical Society · 2006 · 390 citations

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