Concepedia

Author

Frank T. Zenke

Merck (Germany)ORCID

Also Known As

F T Zenke, F. T. Zenke, F. Zenke, F.T. Zenke, Frank T Zenke, Frank T. Zenke, Frank Tadashi. Zenke, Frank ZENKE, Frank Zenke, Zenke, Frank

345

Publications

3.8K

Citations

27

H-Index

72

Concepts

All Affiliations

Merck (Germany)Ono Pharmaceutical (United States)Scripps Research InstituteUniversity Hospital HeidelbergHeidelberg University
FT

About

Frank T. Zenke is an author at Merck (Germany) specializing in medicine, cell biology, and radiation oncology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

19

25

1.8K

2

Natural Sciences

12

12

1.4K

3

Biochemistry

9

9

675

4

Engineering

1

1

172

5

Health Sciences

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18

Frank T. Zenke

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48

Publications

3.6K

Citations

27

H-Index

YearCitations

Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton

Mira Krendel, Frank T. Zenke, Gary Bokoch

Nature Cell Biology

2002

659

Nitric Oxide Destroys Zinc-Sulfur Clusters Inducing Zinc Release from Metallothionein and Inhibition of the Zinc Finger-Type Yeast Transcription Activator LAC9

K D Kröncke, Karin Fehsel, Thorsten Schmidt,

Biochemical and Biophysical Research Communications

1994

278

Identification of a Central Phosphorylation Site in p21-activated Kinase Regulating Autoinhibition and Kinase Activity

Frank T. Zenke, Charles C. King, Benjamin P. Bohl,

Journal of Biological Chemistry

1999

240

p21-activated Kinase (PAK1) Is Phosphorylated and Activated by 3-Phosphoinositide-dependent Kinase-1 (PDK1)

Charles C. King, Elisabeth Gardiner, Frank T. Zenke,

Journal of Biological Chemistry

2000

236

p21-activated Kinase 1 Phosphorylates and Regulates 14-3-3 Binding to GEF-H1, a Microtubule-localized Rho Exchange Factor

Frank T. Zenke, Mira Krendel, Céline DerMardirossian,

Journal of Biological Chemistry

2004

174

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

Anish Thomas, Nobuyuki Takahashi, Vinodh N. Rajapakse,

Cancer Cell

2021

172

Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models

Frank T. Zenke, Astrid Zimmermann, Christian Sirrenberg,

Molecular Cancer Therapeutics

2020

158

Activation of Gal4p by Galactose-Dependent Interaction of Galactokinase and Gal80p

Frank T. Zenke, Reinhard Engels, V. Vollenbroich,

Science

1996

143

αPix Stimulates p21-activated Kinase Activity through Exchange Factor-dependent and -independent Mechanisms

R. Hugh Daniels, Frank T. Zenke, Gary Bokoch

Journal of Biological Chemistry

1999

121

Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate

James D. Orth, Yangzhong Tang, Clement T. Loy,

Molecular Cancer Therapeutics

2008

118

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