Concepedia

Christina Esdar

CE

Statistics

Publications

29

Citations

1.4K

H-Index

21

Active since

1998

Affiliations

Merck KGaA, Darmstadt (Germany)(Current)

Institute of Cancer Research

Cancer Research UK

Cardiff University

Johannes Gutenberg University Mainz

Christina Esdar is an author at Merck KGaA, Darmstadt (Germany) specializing in pharmacology, drug discovery, and medicinal chemistry.

ORCID

Publications per year

1998–2023

29

Publications

29

A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease

Trevor Dale, Paul A. Clarke, Christina Esdar et al. · Nature Chemical Biology · 2015 · 146 citations

, , +11

Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19

Aurélie Mallinger, Kai Schiemann, Christian Rink et al. · Journal of Medicinal Chemistry · 2016 · 112 citations · Full text

, , +16

Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening

Paul Czodrowski, Aurélie Mallinger, Dirk Wienke et al. · Journal of Medicinal Chemistry · 2016 · 111 citations · Full text

, , +13

Production of Ceramides Causes Apoptosis during Early Neural Differentiation in Vitro

Thomas Herget, Christina Esdar, Silke A. Oehrlein et al. · Journal of Biological Chemistry · 2000 · 98 citations · Full text

, , +15

Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases

Paul A. Clarke, Maria-Jesus Ortiz-Ruiz, Robert te Poele et al. · eLife · 2016 · 95 citations · Full text

, , +11

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