Paul Czodrowski

PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations

T. J. Dolinsky, Paul Czodrowski, Hui Li et al. · Nucleic Acids Research · 2007 · 2K citations · Full text

Large-Scale Assessment of Binding Free Energy Calculations in Active Drug Discovery Projects

Christina Schindler, Hannah M. Baumann, Andreas Blum et al. · Journal of Chemical Information and Modeling · 2020 · 292 citations

A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease

Trevor Dale, Paul A. Clarke, Christina Esdar et al. · Nature Chemical Biology · 2015 · 139 citations · Full text

Molecular Immunology, Signal Transduction, Receptor Tyrosine Kinase +7

Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19

Aurélie Mallinger, Kai Schiemann, Christian Rink et al. · Journal of Medicinal Chemistry · 2016 · 110 citations · Full text

Vivo Metabolic Clearance, Medicinal Chemistry, Signaling Pathway +18

Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening

Paul Czodrowski, Aurélie Mallinger, Dirk Wienke et al. · Journal of Medicinal Chemistry · 2016 · 106 citations · Full text

Drug Target, Structure-based Optimization, Excellent Kinase Selectivity +20