Concepedia

An albumin-mediated cholesterol design-based strategy for tuning siRNA pharmacokinetics and gene silencing

Konrad Bieńk, Michael Lykke Hvam, Malgorzata Maria Pakula, Frederik Dagnæs‐Hansen, Jesper Wengel, Birgitte M. Malle, Ulrich Kragh‐Hansen, Jason Cameron, Jens T. Bukrinski, Kenneth A. Howard

Journal of Controlled Release · 2016 · 38 citations · 28 references

DOI

Concepts

References

28

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.3K citations · Full text

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

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RNAi-mediated gene silencing in non-human primates

Tracy Zimmermann, Amy C. H. Lee, Akin Akinc et al. · Nature · 2006 · 1.3K citations

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Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

Adam D. Judge, Vandana Sood, Janet R. Shaw et al. · Nature Biotechnology · 2005 · 1.3K citations

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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

Akin Akinc, Andreas Zumbuehl, Michael S. Goldberg et al. · Nature Biotechnology · 2008 · 1.2K citations

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