Albumin-based drug delivery: harnessing nature to cure disease

Maja Thim Larsen, Matthias Kuhlmann, Michael Lykke Hvam, +1

Molecular and Cellular Therapies

Comparative analysis of discrete exosome fractions obtained by differential centrifugation

Dennis K. Jeppesen, Michael Lykke Hvam, Bjarke Primdahl‐Bengtson, +6

Journal of Extracellular Vesicles

Pellet‐free isolation of human and bovine milk extracellular vesicles by size‐exclusion chromatography

Kristine Blans, M. Hansen, Laila Vestergaard Sørensen, +6

Journal of Extracellular Vesicles

Milk Ev IsolatesEngineeringBiochemistryHuman LactationBioanalysis +12

miRNA profiling of circulating EpCAM⁺ extracellular vesicles: promising biomarkers of colorectal cancer

Marie S. Ostenfeld, Steffen Grann Jensen, Dennis K. Jeppesen, +10

Journal of Extracellular Vesicles

Extracellular VesiclesTumor BiologyOncologyMedicineBiomarker Target +13

Tumour exosomes display differential mechanical and complement activation properties dependent on malignant state: implications in endothelial leakiness

Bradley Whitehead, Linping Wu, Michael Lykke Hvam, +6

Journal of Extracellular Vesicles

Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin

Esben Gjerløff Wedebye Schmidt, Michael Lykke Hvam, Filipa Antunes, +5

Journal of Biological Chemistry

Signal TransductionCellular RecyclingDirect DemonstrationCell TraffickingEndocytic Pathway +9

Fatty Acid-Modified Gapmer Antisense Oligonucleotide and Serum Albumin Constructs for Pharmacokinetic Modulation

Michael Lykke Hvam, Yunpeng Cai, Frederik Dagnæs‐Hansen, +4

Molecular Therapy

An albumin-mediated cholesterol design-based strategy for tuning siRNA pharmacokinetics and gene silencing

Konrad Bieńk, Michael Lykke Hvam, Malgorzata Maria Pakula, +7

Journal of Controlled Release

Lipid PreparationOxysterolLipid SynthesisMedicineSirna Pharmacokinetics +5

The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria

Stig Hill Christiansen, Ronan A. Murphy, Kristian Juul‐Madsen, +15

Scientific Reports

The random co-polymer glatiramer acetate rapidly kills primary human leukocytes through sialic-acid-dependent cell membrane damage

Stig Hill Christiansen, Xianwei Zhang, Kristian Juul‐Madsen, +9

Biochimica et Biophysica Acta (BBA) - Biomembranes

InflammationAutoimmune DiseaseImmunotoxicologyGranulocyteImmunology +7