Concepedia

Lipid Composition Optimization

Lipid Composition Optimization is a methodological framework in pharmaceutical nanotechnology that systematically refines the molar ratios and types of lipids in liposomal formulations to enhance the stability, transfection efficiency, and biocompatibility of lipid-based gene carriers.

369

Publications

21K

Citations

1.8K

Authors

641

Institutions

Publications per year

2017–2026

188

Parents

Publications

369

Rational design of cationic lipids for siRNA delivery

Sean C. Semple, Akin Akinc, Jianxin Chen et al. · Nature Biotechnology · 2010 · 1.8K citations

, , +16

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

Joseph Zabner, A Fasbender, Tom Moninger et al. · Journal of Biological Chemistry · 1995 · 1.4K citations · Full text

, , +16

Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs

Kevin Kauffman, J. Robert Dorkin, Jung Hoon Yang et al. · Nano Letters · 2015 · 768 citations

, , +17

Improved methods to isolate and subfractionate rat liver mitochondria. Lipid composition of the inner and outer membrane

Ruud Hovius, Hilde Lambrechts, Klaas Nicolay et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1990 · 357 citations · Full text

, , +14

Optimization of Physiological Lipid Mixtures for Barrier Repair

Mao‐Qiang Man, Kenneth R. Feingold, Carl Thornfeldt et al. · Journal of Investigative Dermatology · 1996 · 287 citations · Full text

, , +14

1–5 of 369

Authors

1.8K

  1. JV
    Jaleh Varshosaz

    Isfahan University of Medical Sciences, Iran

    7 publications · 452 citations

    7

    h-index

  2. SS
    Syed Sarim Imam

    King Saud University, Saudi Arabia

    5 publications · 185 citations

    5

    h-index

  3. OP
    Om Prakash Katare

    Panjab University, India

    4 publications · 196 citations

    4

    h-index

  4. CA
    Clive A. Prestidge

    University of South Australia, Australia

    4 publications · 131 citations

    4

    h-index

  5. AM
    Amélia M. Silva

    University of Trás-os-Montes and Alto Douro, Portugal

    3 publications · 265 citations

    3

    h-index

1–5 of 1.8K

Institutions

641

  1. Jamia Hamdard

    New Delhi, India

    11 h-index

    44 publications

    1.3K citations

  2. King Saud University

    Riyadh, Saudi Arabia

    8 h-index

    14 publications

    499 citations

  3. Cairo University

    Giza, Egypt

    7 h-index

    11 publications

    571 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    35 publications

    2.8K citations

  5. University of Coimbra

    Coimbra, Portugal

    7 h-index

    25 publications

    1.3K citations

  6. Isfahan University of Medical Sciences

    Isfahan, Iran

    6 h-index

    13 publications

    940 citations

  7. King Abdulaziz University

    Jeddah, Saudi Arabia

    6 h-index

    26 publications

    730 citations

  8. University of Southern Denmark

    Odense, Denmark

    5 h-index

    10 publications

    375 citations

1–8 of 641

Venues

  1. International Journal of Pharmaceutics

    18 publications · 886 citations

    16

    h-index

  2. Pharmaceutics

    13 publications · 467 citations

    12

    h-index

  3. Food Chemistry

    11 publications · 633 citations

    11

    h-index

  4. Journal of Drug Delivery Science and Technology

    JDDST · 10 publications · 249 citations

    10

    h-index

  5. Journal of Liposome Research

    10 publications · 618 citations

    10

    h-index

1–5