Efficient gene transfer into the CNS by lentiviral vectors purified by anion exchange chromatography

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

Luigi Naldini, Ulrike Blömer, Philippe Gallay et al. · Science · 1996 · 4.9K citations

Pharmacy, Biotechnology, Molecular Medicine +14

Production of high-titer helper-free retroviruses by transient transfection.

Warren S. Pear, Garry P. Nolan, Martin Scott et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations

Life Sciences, Biotechnology, Molecular Genetics +14

Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery

Romain Zufferey, Thomas J. Dull, Ronald J. Mandel et al. · Journal of Virology · 1998 · 1.8K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.

Luigi Naldini, Ulrike Blömer, Fred H. Gage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations · Full text

Pharmacy, Biotechnology, Molecular Biology +17

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells.

Jane C. Burns, T Friedmann, Wolfgang Driever et al. · Proceedings of the National Academy of Sciences · 1993 · 1.4K citations

Life Sciences, Biotechnology, Molecular Biology +17