In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

Luigi Naldini, Ulrike Blömer, Philippe Gallay, +5

Science

ImmunologyRetroviral Vector SystemGene DeliveryBiomedical EngineeringStable Transduction +15

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

Philippe Gallay, Thomas J. Hope, Daniel J. Chin, +1

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyHiv-1 Preintegration ComplexHuman RetrovirusResistance Mutation (Virology) +17

HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase

Philippe Gallay, Simon Swingler, Jinping Song, +2

Cell

Viral ReplicationSignal TransductionPhosphotyrosine-mediated BindingNatural SciencesHuman Retrovirus +10

Active Site Residues of Cyclophilin A Are Crucial for Its Signaling Activity via CD147

Vyacheslav Yurchenko, Gabriele Zybarth, Matthew J. O’Connor, +9

Journal of Biological Chemistry

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator

Philippe Gallay, Simon Swingler, Christopher Aiken, +1

Cell

Viral ReplicationViral PersistenceViral Matrix ProteinHuman RetrovirusImmunology +9

Interferon gamma receptor deficient mice are resistant to endotoxic shock.

Bruce D. Car, Vicki M. Eng, Bruno Schnyder, +6

The Journal of Experimental Medicine

ImmunotoxicologyInnate Immune SystemImmunologyImmune RegulationImmunologic Mechanism +17

Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import

Philippe Gallay, V Stitt, Catherine Mundy, +2

Journal of Virology

Viral ReplicationNuclear ImportSignal TransductionMedicineHuman Retrovirus +12

Syndecans Serve as Attachment Receptors for Human Immunodeficiency Virus Type 1 on Macrophages

Andrew C. S. Saphire, Michael Bobardt, Zhe Zhang, +2

Journal of Virology

The cyclophilin inhibitor Debio-025 shows potent anti–hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus

Robert Flisiak, Andrzej Horban, Philippe Gallay, +13

Hepatology

Control of lipopolysaccharide (LPS) binding and LPS-induced tumor necrosis factor secretion in human peripheral blood monocytes

Didier Heumann, Philippe Gallay, C Barras, +5

The Journal of Immunology