High-Level Transduction and Gene Expression in Hematopoietic Repopulating Cells Using a Human Imunodeficiency Virus Type 1-Based Lentiviral Vector Containing an Internal Spleen Focus Forming Virus Promoter

Christophe Demaison, Kathryn L. Parsley, Gaby Brouns, +5

Human Gene Therapy

Hematopoietic Repopulating CellsViral ReplicationImmunologySpleen FocusImmunotherapy +15

Expression of the miR-17-92 polycistron in chronic myeloid leukemia (CML) CD34+ cells

Letizia Venturini, Karin Battmer, M. Castoldi, +6

Blood

Specific inhibition of bcr-abl gene expression by small interfering RNA

Michaela Scherr, Karin Battmer, Thomas Winkler, +3

Blood

LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia

Julia Skokowa, Gunnar Cario, Murat Uenalan, +11

Nature Medicine

InflammationAutoimmune DiseaseNeutrophil GranulocytopoiesisGranulocyteHematology +8

Lentivirus-mediated antagomir expression for specific inhibition of miRNA function

Michaela Scherr, Letizia Venturini, Karin Battmer, +5

Nucleic Acids Research

Micro RnasMirna FunctionRegulate Gene ExpressionEngineeringViral Immunity +12

Enhanced sensitivity to inhibition of SHP2, STAT5, and Gab2 expression in chronic myeloid leukemia (CML)

Michaela Scherr, Anuhar Chaturvedi, Karin Battmer, +4

Blood

Modulation of Gene Expression by Lentiviral-Mediated Delivery of Small Interfering RNA

Michaela Scherr, Karin Battmer, Arnold Ganser, +1

Cell Cycle

A positive feedback loop between IL-1β, LPS and NEU1 may promote atherosclerosis by enhancing a pro-inflammatory state in monocytes and macrophages

Irina Sieve, Melanie Ricke‐Hoch, Martina Kasten, +7

Vascular Pharmacology

InflammationCytokineInflammatory DiseasePro-inflammatory StateCell Signaling +13

Monitoring of BCR-ABL expression using real-time RT-PCR in CML after bone marrow or peripheral blood stem cell transplantation

Matthias Eder, Karin Battmer, Sabine Kafert, +3

Leukemia

Hematological MalignancyCell TherapyTransplantationStem Cell TransplantationImmunology +10

Efficient gene transfer into the CNS by lentiviral vectors purified by anion exchange chromatography

Michaela Scherr, Karin Battmer, Matthias Eder, +5

Gene Therapy

Efficient Gene TransferViral ReplicationXenotransplantationEngineeringSynthetic Virology +12