Kathryn L. Parsley

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

Steven J. Howe, Marc R. Mansour, Kerstin Schwarzwaelder et al. · Journal of Clinical Investigation · 2008 · 1.3K citations · Full text

Medicine, Genetics, Oncology +13

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

H. Bobby Gaspar, Kathryn L. Parsley, Steven J. Howe et al. · The Lancet · 2004 · 684 citations

Medicine, Immunology, Molecular Genetics +17

High-Level Transduction and Gene Expression in Hematopoietic Repopulating Cells Using a Human Imunodeficiency Virus Type 1-Based Lentiviral Vector Containing an Internal Spleen Focus Forming Virus Promoter

Christophe Demaison, Kathryn L. Parsley, Gaby Brouns et al. · Human Gene Therapy · 2002 · 491 citations

Life Sciences, Cell Biology, Molecular Biology +13

Hematopoietic Stem Cell Gene Therapy for Adenosine Deaminase–Deficient Severe Combined Immunodeficiency Leads to Long-Term Immunological Recovery and Metabolic Correction

H. Bobby Gaspar, Samantha Cooray, Kimberly Gilmour et al. · Science Translational Medicine · 2011 · 284 citations · Full text

Medicine, Hematology, Immunology +17

Long-Term Persistence of a Polyclonal T Cell Repertoire After Gene Therapy for X-Linked Severe Combined Immunodeficiency

H. Bobby Gaspar, Samantha Cooray, Kimberly Gilmour et al. · Science Translational Medicine · 2011 · 233 citations · Full text

Medicine, Hematology, Immunology +15