Concepedia

Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis

Xinjian Li, Yuhui Jiang, Jill Meisenhelder, Weiwei Yang, David H. Hawke, Yanhua Zheng, Yan Xia, Kenneth Aldape, Jie He, Tony Hunter,

Molecular Cell · 2016 · 502 citations · 33 references

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33

HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.9K citations · Full text

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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

Ioanna Papandreou, Rob A. Cairns, Lucrezia Fontana et al. · Cell Metabolism · 2006 · 2.2K citations · Full text

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Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

Weiwei Yang, Yan Xia, Haitao Ji et al. · Nature · 2011 · 1K citations · Full text

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ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

Weiwei Yang, Yanhua Zheng, Yan Xia et al. · Nature Cell Biology · 2012 · 915 citations · Full text

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Glucose Deprivation Contributes to the Development of <i>KRAS</i> Pathway Mutations in Tumor Cells

Jihye Yun, Carlo Rago, Ian Cheong et al. · Science · 2009 · 909 citations · Full text

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