Concepedia

PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease

Kuti Baruch, Aleksandra Deczkowska, Neta Rosenzweig, Afroditi Tsitsou-Kampeli, Alaa Sharif, Orit Matcovitch-Natan, Alexander Kertser, Eyal David, Ido Amit, Michal Schwartz

Nature Medicine · 2016 · 416 citations · 15 references

DOI

Concepts

References

15

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

Sven Heinz, Christopher Benner, Nathanael J. Spann et al. · Molecular Cell · 2010 · 14.6K citations · Full text

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TopHat: discovering splice junctions with RNA-Seq

Cole Trapnell, Lior Pachter, Steven L. Salzberg · Bioinformatics · 2009 · 12.1K citations · Full text

, , +16

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Holly D. Oakley, Sarah L. Cole, Sreemathi Logan et al. · Journal of Neuroscience · 2006 · 3.6K citations · Full text

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Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

Diego Adhemar Jaitin, Ephraim Kenigsberg, Hadas Keren‐Shaul et al. · Science · 2014 · 1.9K citations · Full text

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Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson et al. · Human Molecular Genetics · 2003 · 1.6K citations · Full text

, , +16