Host microbiota constantly control maturation and function of microglia in the CNS

Daniel Erny, Anna Lena Hrabě de Angelis, Diego Adhemar Jaitin, +17

Nature Neuroscience

Host ResponseMedicineMicrobiotaImmunologyBrain-immune Interaction +6

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

Diego Adhemar Jaitin, Ephraim Kenigsberg, Hadas Keren‐Shaul, +8

Science

m ⁶ A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

Shay Geula, Sharon Moshitch-Moshkovitz, Dan Dominissini, +28

Science

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

Diego Adhemar Jaitin, Lorenz Adlung, Christoph A. Thaiss, +20

Cell

InflammationMetabolic SyndromePhysiologyAutophagyImmunology +6

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

Franziska Paul, Ya’ara Arkin, Amir Giladi, +19

Cell

Developmental BiologyGeneticsTranscription RegulationLineage CommitmentGene Expression +4

Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations

Christoph A. Thaiss, Maayan Levy, Tal Korem, +22

Cell

BiologyMedicineMicrobial EcologyMicrobiomeSystems Biology +2

Chromatin state dynamics during blood formation

David Lara‐Astiaso, Assaf Weiner, Erika Lorenzo-Vivas, +9

Science

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

Diego Adhemar Jaitin, Assaf Weiner, Ido Yofe, +7

Cell

Functional GenomicsSingle Cell SequencingMedicineImmunologySingle-cell Genomics +7

Deterministic direct reprogramming of somatic cells to pluripotency

Yoach Rais, Asaf Zviran, Shay Geula, +23

Nature

Induced Pluripotent Stem CellDevelopmental BiologyCell ReprogrammingGenetic EngineeringDeterministic Direct Reprogramming +3

Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer

Yonatan Katzenelenbogen, Fadi Sheban, Adam Yalin, +13

Cell

MedicineImmunologyRegulatory T CellsLong Non-coding RnaImmunosuppressive Role +7