Host microbiota constantly control maturation and function of microglia in the CNS

Daniel Erny, Anna Lena Hrabě de Angelis, Diego Adhemar Jaitin, +17

Nature Neuroscience

Host ResponseMedicineMicrobiotaImmunologyBrain-immune Interaction +6

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

Katrin Kierdorf, Daniel Erny, Tobias Goldmann, +19

Nature Neuroscience

InflammationSignal TransductionMicroglia EmergeMedicineImmunology +6

Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program

Laufey Geirsdóttir, Eyal David, Hadas Keren‐Shaul, +25

Cell

Primate Microglia ProgramMedicineSingle-cell BiologyImmunologySingle-cell Genomics +6

Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease

Daniel Erny, Nikolaos Dokalis, Charlotte Mezö, +17

Cell Metabolism

InflammationHost-microbe InteractionsBlood–brain BarrierMedicineMicrobiota +13

Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer's Disease

Alexander Mildner, Bernhard Schlevogt, Katrin Kierdorf, +9

Journal of Neuroscience

TAK1 Suppresses a NEMO-Dependent but NF-κB-Independent Pathway to Liver Cancer

Kira Bettermann, Mihael Vucur, Johannes Haybaeck, +23

Cancer Cell

HepatologyCell SignalingLiver PhysiologyMedicineImmunology +8

Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine

Omar Mossad, Bérénice Batut, Bahtiyar Yılmaz, +16

Nature Neuroscience

InflammationDysbiosisMitochondrial DamageAge-related Oxidative StressMedicine +12

Microglia contribute to the propagation of Aβ into unaffected brain tissue

Paolo d’Errico, Stephanie Ziegler‐Waldkirch, Vanessa Aires, +13

Nature Neuroscience

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

Laura Herrtwich, Indrajit Nanda, Konstantinos Evangelou, +34

Cell

Cell DivisionGranulocyteImmunologyCell DeathMedicine +3

Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease

Charlotte Mezö, Nikolaos Dokalis, Omar Mossad, +12

Acta Neuropathologica Communications