Nature Biotechnology · 2016 · 871 citations · 38 references
Life SciencesBiotechnologyMolecular BiologyGene DeliveryGene TherapyGenome EditingCrispr-cas SystemsDelivery Systems For Genome EditingGene Editing Payload DeliveryIn Vivo Gene DeliveryIn Vivo Gene TherapyTherapeutic Genome EditingCrispr-based Genome EngineeringCrispr-cas Genome EditingDelivery Systems For CrisprGene Editing Delivery VectorsGenome Editing DeliveryGenome Editing Via Viral VectorsIn Vivo Genome Editing
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Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text
DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Luke A. Gilbert, Matthew H. Larson, Leonardo Morsut et al. · Cell · 2013 · 3.8K citations · Full text
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Yanfang Fu, Jennifer A Foden, Cyd Khayter et al. · Nature Biotechnology · 2013 · 3.3K citations · Full text