Concepedia

Hyperglycemia‐Mediated Oxidative Stress Increases Pulmonary Vascular Permeability

John S. Clemmer, Lusha Xiang, Silu Lu, Peter N. Mittwede, Robert L. Hester

Microcirculation · 2016 · 28 citations · 53 references

DOIFull text

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Abstract

These data suggest that hyperglycemia in metabolic syndrome exacerbates lung vascular permeability through increases in vascular superoxide, possibly through NADPH oxidase.

References

53

Mitochondrial formation of reactive oxygen species

Julio F. Turrens · The Journal of Physiology · 2003 · 3.9K citations

Vitamin E Consumption and the Risk of Coronary Heart Disease in Men

Eric B. Rimm, Meir J. Stampfer, Alberto Ascherio et al. · New England Journal of Medicine · 1993 · 2.4K citations · Full text

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

Mark R. Owen, E. Doran, Andrew P. Halestrap · Biochemical Journal · 2000 · 2.1K citations · Full text

Mitochondrial Complex I Inhibitor Rotenone Induces Apoptosis through Enhancing Mitochondrial Reactive Oxygen Species Production

Nianyu Li, Kathy Ragheb, Gretchen Lawler et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

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Mechanism by which metformin reduces glucose production in type 2 diabetes.

Ripudaman S. Hundal, Martin Krššák, Sylvie Dufour et al. · Diabetes · 2000 · 1K citations · Full text