Concepedia

Top-down and bottom-up modeling in system pharmacology to understand clinical efficacy: An example with NRTIs of HIV-1

Sulav Duwal, Max von Kleist

European Journal of Pharmaceutical Sciences · 2016 · 31 citations · 50 references

DOI

Concepts

References

50

Viral dynamics in human immunodeficiency virus type 1 infection

Xiping Wei, Sajal K. Ghosh, Maria E. Taylor et al. · Nature · 1995 · 3.3K citations

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A Novel Phenotypic Drug Susceptibility Assay for Human Immunodeficiency Virus Type 1

Christos J. Petropoulos, Neil Parkin, Kay Limoli et al. · Antimicrobial Agents and Chemotherapy · 2000 · 653 citations

, , +17

The stoichiometry of Gag protein in HIV-1

John A. G. Briggs, Martha N. Simon, Ingolf Gross et al. · Nature Structural & Molecular Biology · 2004 · 525 citations

, , +12

A Novel Antiviral Intervention Results in More Accurate Assessment of Human Immunodeficiency Virus Type 1 Replication Dynamics and T-Cell Decay In Vivo

Martin Markowitz, Michael J. Louie, Arlene Hurley et al. · Journal of Virology · 2003 · 402 citations · Full text

, , +15

A Rapid Method for Simultaneous Detection of Phenotypic Resistance to Inhibitors of Protease and Reverse Transcriptase in Recombinant Human Immunodeficiency Virus Type 1 Isolates from Patients Treated with Antiretroviral Drugs

Kurt Hertogs, Marie‐Pierre de Béthune, Veronica Miller et al. · Antimicrobial Agents and Chemotherapy · 1998 · 391 citations · Full text

, , +17