Concepedia

Disease-state Modeling

Disease-State Modeling is a type of Physiologically Based Pharmacokinetic Modeling that specifically incorporates pathophysiological alterations associated with a particular disease to predict how the disease affects the absorption, distribution, metabolism, and excretion of drugs.

194

Publications

11.6K

Citations

897

Authors

465

Institutions

Publications per year

2017–2026

55

Variants

Disease-state Pbpk Modeling

Parents

Publications

194

System Dynamics Modeling for Public Health: Background and Opportunities

Jack Homer, Gary Hirsch · American Journal of Public Health · 2006 · 977 citations · Full text

, , +17

The NCBI BioSystems database

Lewis Y. Geer, Aron Marchler‐Bauer, Renata C. Geer et al. · Nucleic Acids Research · 2009 · 904 citations · Full text

, , +17

Automated inference of molecular mechanisms of disease from amino acid substitutions

Biao Li, Vidhya G. Krishnan, Matthew Mort et al. · Bioinformatics · 2009 · 846 citations · Full text

, , +9

OARSI-FDA initiative: defining the disease state of osteoarthritis

Nancy E. Lane, K D Brandt, Gillian Hawker et al. · Osteoarthritis and Cartilage · 2011 · 384 citations · Full text

, , +14

A Markov Model for Analysing Cancer Markers and Disease States in Survival Studies

Biometrics · 1986 · 296 citations

, , +17

1–5 of 194

Authors

897

  1. JL
    Jyrki Lötjönen

    VTT Technical Research Centre of Finland, Finland

    8 publications · 313 citations

    8

    h-index

  2. JM
    Jussi Mattila

    VTT Technical Research Centre of Finland, Finland

    6 publications · 283 citations

    6

    h-index

  3. LC
    Luonan Chen

    Chinese Academy of Sciences, China

    6 publications · 518 citations

    6

    h-index

  4. HS
    Hilkka Soininen

    University of Eastern Finland, Finland

    5 publications · 240 citations

    5

    h-index

  5. JK
    Juha Koikkalainen

    VTT Technical Research Centre of Finland, Finland

    5 publications · 214 citations

    5

    h-index

1–5 of 897

Institutions

465

  1. University of California, Los Angeles

    Los Angeles, United States

    5 h-index

    22 publications

    778 citations

  2. University of California, Davis

    Davis, United States

    5 h-index

    13 publications

    1.4K citations

  3. VTT Technical Research Centre of Finland

    Espoo, Finland

    5 h-index

    20 publications

    1.2K citations

  4. King's College London

    London, United Kingdom

    4 h-index

    8 publications

    301 citations

  5. University of Michigan

    Ann Arbor, United States

    4 h-index

    9 publications

    599 citations

  6. University of Eastern Finland

    Joensuu, Finland

    4 h-index

    28 publications

    1.2K citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    4 h-index

    19 publications

    699 citations

  8. University of Washington

    Seattle, United States

    4 h-index

    5 publications

    525 citations

1–8 of 465

Venues

  1. PLoS ONE

    9 publications · 326 citations

    9

    h-index

  2. Bioinformatics

    6 publications · 1.1K citations

    6

    h-index

  3. Statistics in Medicine

    6 publications · 209 citations

    6

    h-index

  4. PubMed

    Repository · 6 publications · 102 citations

    6

    h-index

  5. Scientific Reports

    5 publications · 308 citations

    5

    h-index

1–5