Pharmacometric Simulations is a quantitative modeling and simulation technique within pharmacometrics that integrates pharmacokinetic, pharmacodynamic, and disease progression models to predict the time-course and magnitude of drug effects in patients, distinguishing it from general clinical trial simulations by its reliance on nonlinear mixed-effects models to characterize population-level variability and exposure-response relationships.
180
Publications
9.8K
Citations
761
Authors
322
Institutions
Publications per year
2017–2026
60
Parents
Publications
180
Michael Neely, Michael G. van Guilder, Walter M. Yamada et al. · Therapeutic Drug Monitoring · 2012 · 474 citations · Full text
1–5 of 180
Authors
761
- AR
7
h-index
- MO
7
h-index
- PG
6
h-index
- LE
4
h-index
- EM
4
h-index
1–5 of 761
Institutions
322
Uppsala University
Uppsala, Sweden
13 h-index
43 publications
3.4K citations
Center for Drug Evaluation and Research
Silver Spring, United States
9 h-index
27 publications
992 citations
Pfizer (United States)
New York, United States
7 h-index
20 publications
2.1K citations
University of Manchester
Manchester, United Kingdom
7 h-index
11 publications
554 citations
Bristol-Myers Squibb (United States)
New York, United States
6 h-index
16 publications
718 citations
Pfizer (United Kingdom)
Tadworth, United Kingdom
6 h-index
9 publications
445 citations
Simcyp (United Kingdom)
Sheffield, United Kingdom
6 h-index
17 publications
2K citations
Roche (Switzerland)
Basel, Switzerland
5 h-index
7 publications
416 citations
1–8 of 322
Venues
- CPT Pharmacometrics & Systems Pharmacology
PSP · 30 publications · 3.4K citations
19
h-index
- Clinical Pharmacology & Therapeutics
CPT · 11 publications · 528 citations
11
h-index
- The Journal of Clinical Pharmacology
8 publications · 204 citations
8
h-index
- British Journal of Clinical Pharmacology
BJCP · 6 publications · 337 citations
6
h-index
- Journal of Pharmacokinetics and Pharmacodynamics
6 publications · 184 citations
6
h-index
1–5