Concepedia

Evaluation of two dynamic in vitro models simulating fasted and fed state conditions in the upper gastrointestinal tract (TIM-1 and tiny-TIM) for investigating the bioaccessibility of pharmaceutical compounds from oral dosage forms

Miriam Verwei, Mans Minekus, Evelijn Zeijdner, Ronald Schilderink, R. Havenaar

International Journal of Pharmaceutics · 2015 · 117 citations · 35 references

DOI

Concepts

References

35

Molecular Properties of WHO Essential Drugs and Provisional Biopharmaceutical Classification

Nehal A. Kasim, Marc Whitehouse, Chandrasekharan Ramachandran et al. · Molecular Pharmaceutics · 2003 · 844 citations

, , +16

A Multicompartmental Dynamic Computer-controlled Model Simulating the Stomach and Small Intestine

Mans Minekus, Phillipe Marteau, R. Havenaar et al. · Alternatives to Laboratory Animals · 1995 · 667 citations

, , +17

A computer-controlled system to simulate conditions of the large intestine with peristaltic mixing, water absorption and absorption of fermentation products

Mans Minekus, M. Smeets-Peeters, Annick Bernalier et al. · Applied Microbiology and Biotechnology · 1999 · 453 citations

, , +14

Pharmacokinetics and Absorption of Posaconazole Oral Suspension under Various Gastric Conditions in Healthy Volunteers

Gopal Krishna, Allen Moton, Lei Ma et al. · Antimicrobial Agents and Chemotherapy · 2008 · 350 citations

, , +16

Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults

Rachel Courtney, David Wexler, Elaine Radwanski et al. · British Journal of Clinical Pharmacology · 2003 · 325 citations · Full text

, , +17