Concepedia

Physiologically Based Absorption Modeling

Physiologically Based Absorption Modeling is a computational modeling framework that simulates drug absorption processes by integrating anatomical, physiological, biochemical, and physicochemical parameters to predict the rate and extent of drug bioavailability in the gastrointestinal tract.

392

Publications

20.9K

Citations

1.3K

Authors

420

Institutions

Publications per year

2017–2026

75

Variants

Pbam

Parents

Publications

392

Characterization of the Human Upper Gastrointestinal Contents Under Conditions Simulating Bioavailability/Bioequivalence Studies

Lida Kalantzi, Konstantinos Goumas, V. Kalioras et al. · Pharmaceutical Research · 2005 · 653 citations

, , +14

Drug Absorption I: An In Situ Rat Gut Technique Yielding Realistic Absorption Rates

James T. Doluisio, Norman F. Billups, Lewis W. Dittert et al. · Journal of Pharmaceutical Sciences · 1969 · 349 citations

, , +12

<i>In Vitro</i> Models for Studying Secondary Plant Metabolite Digestion and Bioaccessibility

Marie Alminger, Anna-M. Aura, Torsten Bohn et al. · Comprehensive Reviews in Food Science and Food Safety · 2014 · 338 citations · Full text

, , +17

A System Model of Oral Glucose Absorption: Validation on Gold Standard Data

Chiara Dalla Man, Michael Camilleri, Claudio Cobelli · IEEE Transactions on Biomedical Engineering · 2006 · 312 citations

, , +17

Estimating Human Oral Fraction Dose Absorbed: A Correlation Using Rat Intestinal Membrane Permeability for Passive and Carrier-Mediated Compounds

Gordon L. Amidon, Patrick J. Sinko, David Fleisher · Pharmaceutical Research · 1988 · 300 citations · Full text

, , +16

1–5 of 392

Authors

1.3K

  1. JD
    Jennifer Dressman

    Goethe University Frankfurt, Germany

    13 publications · 1.7K citations

    13

    h-index

  2. FK
    Filippos Kesisoglou

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    12 publications · 513 citations

    11

    h-index

  3. NF
    Norman F.H. Ho

    University of Michigan, United States

    11 publications · 726 citations

    10

    h-index

  4. HL
    Hans Lennernäs

    Uppsala University, Sweden

    8 publications · 629 citations

    8

    h-index

  5. NP
    Neil Parrott

    Roche (Switzerland), Switzerland

    8 publications · 603 citations

    8

    h-index

1–5 of 1.3K

Institutions

420

  1. University of Michigan

    Ann Arbor, United States

    20 h-index

    63 publications

    6.2K citations

  2. Uppsala University

    Uppsala, Sweden

    18 h-index

    43 publications

    3K citations

  3. AstraZeneca (Sweden)

    Södertälje, Sweden

    14 h-index

    36 publications

    4.5K citations

  4. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    13 h-index

    26 publications

    1.1K citations

  5. Goethe University Frankfurt

    Frankfurt am Main, Germany

    13 h-index

    30 publications

    3.1K citations

  6. Roche (Switzerland)

    Basel, Switzerland

    11 h-index

    37 publications

    2K citations

  7. Universitat de València

    Valencia, Spain

    11 h-index

    48 publications

    3.3K citations

  8. University of California, San Francisco

    San Francisco, United States

    9 h-index

    17 publications

    488 citations

1–8 of 420

Venues

  1. Pharmaceutical Research

    33 publications · 3.1K citations

    27

    h-index

  2. Journal of Pharmaceutical Sciences

    43 publications · 2.4K citations

    26

    h-index

  3. European Journal of Pharmaceutical Sciences

    31 publications · 2.5K citations

    25

    h-index

  4. International Journal of Pharmaceutics

    22 publications · 1.2K citations

    19

    h-index

  5. Journal of Pharmacokinetics and Biopharmaceutics

    15 publications · 561 citations

    15

    h-index

1–5