Concepedia

Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56lck inhibitors

Jagabandhu Das, Robert V. Moquin, James C. Lin, Chunjian Liu, Arthur M. Doweyko, Henry F. DeFex, Qiong Fang, Suhong Pang, Sidney Pitt, Ding Ren Shen,

Bioorganic & Medicinal Chemistry Letters · 2003 · 106 citations · 9 references

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9

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

Jeffrey H. Hanke, Joseph P. Gardner, Robert L. Dow et al. · Journal of Biological Chemistry · 1996 · 2K citations · Full text

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Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

David B. Straus · Cell · 1992 · 1K citations

, , +16

Profound block in thymocyte development in mice lacking p56lck

Thierry Jo Molina, Kenji Kishihara, David P. Siderovski et al. · Nature · 1992 · 966 citations

, , +9

Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

Hiroto Yamaguchi, Wayne A. Hendrickson · Nature · 1996 · 491 citations

, , +14

A dominant‐negative transgene defines a role for p56lck in thymopoiesis.

Steven D. Levin, Sarah Anderson, Katherine A. Forbush et al. · The EMBO Journal · 1993 · 302 citations · Full text

, , +8