Robert V. Moquin

2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of <i>N</i> -(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent <i>pan</i> -Src Kinase Inhibitor

Jagabandhu Das, Ping Chen, Derek Norris et al. · Journal of Medicinal Chemistry · 2006 · 400 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Selective Itk Inhibitors Block T-Cell Activation and Murine Lung Inflammation

Tai-An Lin, Kim W. McIntyre, Jagabandhu Das et al. · Biochemistry · 2004 · 113 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56lck inhibitors

Jagabandhu Das, Robert V. Moquin, James C. Lin et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 106 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors

Jagabandhu Das, Joseph A. Furch, Chunjian Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Benzazepinone calcium channel blockers. 2. Structure activity and drug metabolism studies leading to potent antihypertensive agents. Comparison with benzothiazepinones

David Floyd, S. David Kimball, John Krapcho et al. · Journal of Medicinal Chemistry · 1992 · 68 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9