Overriding Imatinib Resistance with a Novel ABL Kinase Inhibitor

Neil P. Shah, Chris Tran, Francis Y. Lee, +3

Science

Imatinib ResistanceImatinib-resistant Bcr-abl MutantsChronic Myeloid LeukemiaHematological MalignancyHealth Sciences +12

2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of <i>N</i> -(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent <i>pan</i> -Src Kinase Inhibitor

Jagabandhu Das, Ping Chen, Derek Norris, +18

Journal of Medicinal Chemistry

PBX3 is an important cofactor of HOXA9 in leukemogenesis

Zejuan Li, Zhiyu Zhang, Yuanyuan Li, +21

Blood

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML

Zejuan Li, Hao Huang, Yuanyuan Li, +27

Blood

Phase I Trial of Lenalidomide and CCI-779 in Patients With Relapsed Multiple Myeloma: Evidence for Lenalidomide–CCI-779 Interaction via P-Glycoprotein

Craig C. Hofmeister, Xiaoxia Yang, Flavia Pichiorri, +18

Journal of Clinical Oncology

The Nuclear Factor (Erythroid-derived 2)-like 2 and Proteasome Maturation Protein Axis Mediate Bortezomib Resistance in Multiple Myeloma

Bing-Zong Li, Jinxiang Fu, Ping Chen, +7

Journal of Biological Chemistry

PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the <i>MLL</i> -Rearranged Disease

Zejuan Li, Ping Chen, Rui Su, +16

Cancer Research

Surgicel® (oxidized regenerated cellulose) granuloma mimicking local recurrent gastrointestinal stromal tumor: A case report

Hao Wang, Ping Chen

Oncology Letters

Metformin sensitizes AML cells to chemotherapy through blocking mitochondrial transfer from stromal cells to AML cells

Ruolan You, Bin Wang, Ping Chen, +8

Cancer Letters

Stromal CellsHematological MalignancyOncologyMitochondrial FunctionMitochondrial Dynamic +13

The diagnostic utility of targeted gene panel sequencing in discriminating etiologies of cytopenia

Gang Zheng, Ping Chen, Aparna Pallavajjalla, +7

American Journal of Hematology

High PpvMixed-phenotype Acute LeukemiaGeneticsGenetic EpidemiologyPathology +25