Ding Ren Shen

Disruption of insulin–like growth factor 2 imprinting in Beckwith–Wiedemann syndrome

Rosanna Weksberg, Ding Ren Shen, Yan Ling Fei et al. · Nature Genetics · 1993 · 424 citations

Developmental Biology, Growth Hormone, Human Growth +6

2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of <i>N</i> -(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent <i>pan</i> -Src Kinase Inhibitor

Jagabandhu Das, Ping Chen, Derek Norris et al. · Journal of Medicinal Chemistry · 2006 · 393 citations · Full text

Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56lck inhibitors

Jagabandhu Das, Robert V. Moquin, James C. Lin et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 105 citations · Full text

Potent P56lck Inhibitors, Medicinal Chemistry, Biochemistry +8

Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors

Ashvinikumar V. Gavai, Claude Quesnelle, Derek Norris et al. · ACS Medicinal Chemistry Letters · 2015 · 88 citations · Full text

Solid Tumors, Pharmacotherapy, Tumor Biology +18

Design, Synthesis, and Anti-inflammatory Properties of Orally Active 4-(Phenylamino)-pyrrolo[2,1-<i>f</i>][1,2,4]triazine p38α Mitogen-Activated Protein Kinase Inhibitors

John Hynes, Alaric J. Dyckman, Shuqun Lin et al. · Journal of Medicinal Chemistry · 2007 · 81 citations · Full text