John Hynes - Concepedia

Author

John Hynes

Bristol-Myers Squibb (United States)ORCID

Also Known As

Hynes Jr, John, J. Hynes, John Hynes, John Hynes Jr., John Hynes,, John Hynes, Jr., John Hynes, Jr.,, John Jr. Hynes

Publications

1.5K

Citations

H-Index

Concepts

All Affiliations

Bristol-Myers Squibb (United States)Bristol-Myers Squibb (Germany)Biocon (India)Bristol-Myers Squibb (India)University of Pennsylvania

About

John Hynes is an author at Bristol-Myers Squibb (United States) specializing in pharmacology, medicine, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	18	617
2	Natural Sciences	14	16	538
3	Biochemistry	10	11	396
4	Engineering	4	4	199
5	Allergy	1	1	73

John Hynes

Publications

1.3K

Citations

H-Index

Page 1

	Year	Citations
Modulation of Receptor and Receptor Subtype Affinities Using Diastereomeric and Enantiomeric Monosaccharide Scaffolds as a Means to Structural and Biological Diversity. A New Route to Ether Synthesis Ralph Hirschmann, John Hynes, Maria A. Cichy-Knight, Journal of Medicinal Chemistry	1998	108
Copper-Catalyzed Chlorination of Functionalized Arylboronic Acids Hong Wu, John Hynes Organic Letters Arylboronic AcidsChemical EngineeringCross-coupling ReactionEngineeringCu Catalysis	2010	91
Design, Synthesis, and Anti-inflammatory Properties of Orally Active 4-(Phenylamino)-pyrrolo[2,1-<i>f</i>][1,2,4]triazine p38α Mitogen-Activated Protein Kinase Inhibitors John Hynes, Alaric J. Dyckman, Shuqun Lin, Journal of Medicinal Chemistry	2007	81
<i>N</i>-Amination of Pyrrole and Indole Heterocycles with Monochloramine (NH<sub>2</sub>Cl) John Hynes, Wendel W. Doubleday, Alaric J. Dyckman, The Journal of Organic Chemistry Chemical EngineeringExcellent ReagentPyrrole-containing HeterocyclesEngineeringBiochemistry	2004	79
DBS Sampling Can be Used to Stabilize Prodrugs in Drug Discovery Rodent Studies without the Addition of Esterase Inhibitors Celia D’Arienzo, Qin Ji, Lorell Discenza, Bioanalysis	2010	78
Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity Shailesh Dudhgaonkar, Sourabh Ranade, Jignesh Nagar, The Journal of Immunology ImmunologyImmunologic MechanismInnate ImmunityDermatologyImmunotherapy	2016	73
Synthesis of Potent Cyclic Hexapeptide NK-1 Antagonists. Use of a Minilibrary in Transforming a Peptidal Somatostatin Receptor Ligand into an NK-1 Receptor Ligand via a Polyvalent Peptidomimetic Ralph Hirschmann, Wenqing Yao, Margaret A. Cascieri, Journal of Medicinal Chemistry	1996	60
Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-<i>N</i>-propylpyrrolo[1,2-<i>f</i>][1,2,4]triazine-6-carboxamide (BMS-582949), a Clinical p38α MAP Kinase Inhibitor for the Treatment of Inflammatory Diseases Chunjian Liu, James C. Lin, Stephen T. Wrobleski, Journal of Medicinal Chemistry P38α Enzymatic AssayPharmacotherapyInflammatory ArthritisInflammationMolecular Pharmacology	2010	57
Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties Stephen T. Wrobleski, Ping Chen, John Hynes, Journal of Medicinal Chemistry Combinatorial ChemistryOrally Active IndolopyridonePharmacotherapyBioactive Amide ConformationChemical Biology	2003	57
Discovery of the CCR1 Antagonist, BMS-817399, for the Treatment of Rheumatoid Arthritis Joseph B. Santella, Daniel S. Gardner, John V. Duncia, Journal of Medicinal Chemistry InflammationRheumatologyRheumatoid DisorderCcr1 AntagonistAnti-inflammatory	2014	55

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