Concepedia

Copper-Catalyzed Chlorination of Functionalized Arylboronic Acids

Hong Wu, John Hynes

Organic Letters · 2010 · 91 citations · 34 references

DOI

Concepts

Abstract

A mild, efficient, Cu(I)-catalyzed method for the conversion of arylboronic acids to aryl chlorides is reported. This method is particularly useful for the conversion of electron-deficient arylboronic acids to aryl chlorides, a transformation that is inefficient in the absence of Cu catalysis.

References

34

Modern Synthetic Methods for Copper‐Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation

Steven V. Ley · Angewandte Chemie International Edition · 2003 · 2.5K citations

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Modern Synthetic Methods for Copper‐Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation

Steven V. Ley, Andrew W. Thomas · Angewandte Chemie International Edition · 2004 · 2.1K citations · Full text

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The Development of Versatile Methods for Palladium-Catalyzed Coupling Reactions of Aryl Electrophiles through the Use of P(<i>t</i>-Bu)<sub>3</sub> and PCy<sub>3</sub> as Ligands

Gregory C. Fu · Accounts of Chemical Research · 2008 · 738 citations

, , +13

A Highly Active Catalyst for Pd-Catalyzed Amination Reactions: Cross-Coupling Reactions Using Aryl Mesylates and the Highly Selective Monoarylation of Primary Amines Using Aryl Chlorides

Brett P. Fors, Donald A. Watson, Mark R. Biscoe et al. · Journal of the American Chemical Society · 2008 · 524 citations · Full text

, , +17

Meta Halogenation of 1,3-Disubstituted Arenes via Iridium-Catalyzed Arene Borylation

Jaclyn M. Murphy, Xuebin Liao, John F. Hartwig · Journal of the American Chemical Society · 2007 · 404 citations

, , +11