Concepedia

Deregulation of BRCA1 Leads to Impaired Spatiotemporal Dynamics of γ-H2AX and DNA Damage Responses in Huntington’s Disease

Gye Sun Jeon, Ki Yoon Kim, Yu Jin Hwang, Min-Kyung Jung, Sungkwan An, Mutsuko Ouchi, Toru Ouchi, Neil W. Kowall, Junghee Lee, Hoon Ryu

Molecular Neurobiology · 2012 · 43 citations · 34 references

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34

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

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A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

Tanya T. Paull, Emmy P. Rogakou, Vikky Yamazaki et al. · Current Biology · 2000 · 2.1K citations · Full text

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Genomic Instability in Mice Lacking Histone H2AX

Arkady Celeste, Simone Petersen, Peter Romanienko et al. · Science · 2002 · 1.4K citations · Full text

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MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks

Manuel Stucki, Julie A. Clapperton, Duaa H. Mohammad et al. · Cell · 2005 · 1.1K citations · Full text

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Requirement of ATM-Dependent Phosphorylation of Brca1 in the DNA Damage Response to Double-Strand Breaks

David Cortez, Yi Wang, Jun Qin et al. · Science · 1999 · 1K citations

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